Project Title: Multidisciplinary study of community-acquired sepsis survivors in Latvia

Project No: lzp-2019/1-0225

Period: 1 January 2020 – 31 December 2022

Project costs: 300 000.00 EUR

Principle Investigator: Dr.med. U. Dumpis (University of Latvia)

Collaboration: Dr. biol. Assoc. prof. Jānis Kloviņš (Latvian Biomedical Research and Study Centre)

Summary

This research will explore impacts, needs, and burden of care among sepsis survivors by offering multidisciplinary approach and investigating social, clinical and biological mechanisms causing long-term morbid events. The primary objective of the study is to obtain in-depth understanding on the sepsis survivors, including clinical, molecular aspects of the recovery from illness. Secondary objectives are: 1. Explore the general care pathways and outcomes of sepsis patients using the sepsis register of the PSCUH and National data base. 2. Investigate perceptions, experience and needs of sepsis survivors, their informal and formal caregivers during the post-sepsis recovery. 3. Analyse molecular data using blood and stool samples of sepsis survivors for one year. Exploratory objectives are: 1. Find novel candidate biomarkers for characterization of the course of recovery from sepsis. The research project will not only offer first such study in Latvian context but also provide comprehensive understanding of molecular, clinical, and social pathways of post-sepsis survival.

 Information published 02.01.2020.