Project title: Development of precision medicine approaches for the treatment of pediatric malignant tumors
Project implementation period: October 1, 2025 – December 31, 2025
Total project funding: EUR 198 566,78
Project scientific leader BMC: Dr. biol. Monta Brīvība
Project summary:
The aim of the project is to enhance the competence of healthcare professionals and scientists in the field of pediatric cancer genetics and to promote the development of precision medicine approaches based on molecular research in pediatric oncology clinical practice in Latvia.
Within the framework of the project, biological material (blood, tissue, and fecal samples) will be collected from patients up to 17 years of age (inclusive) diagnosed with malignant tumors or with clinically justified suspicions of such. This will supplement a specific, clinically and genetically characterized pediatric oncology cohort within the Latvian Genome Database (VIGDB). The collected biological material will be used for genomic analyses (whole genome sequencing, transcriptome sequencing, and other large-scale genomic investigations as needed), as well as for future research projects with potential application of the obtained data for diagnostic refinement and improved therapeutic effectiveness.
The project’s outcomes aim to establish a pediatric cancer research resource that will provide additional insights into the mechanisms of tumor pathogenesis in children and contribute to improving healthcare for these patients.
Information published on 07.10.2025.