About us

Jānis Kloviņš , Dr. biol., Assoc. prof.

Deputy chairman
E-mail: klovins@biomed.lu.lv

Projects

• European Regional Development Fund (ERDF), Measure 1.1.1.1 “Support for applied research”
• Interaction and dynamics of intestinal IgA and gut microbiome profile during antidiabetic therapy

Publications

• International

• Age at first birth in women is genetically associated with increased risk of schizophrenia Ni, G., Gratten, J., Wray, N.R.,, J Kloviņš, L Ņikitina-Zaķe, M.J., Sullivan, P.F., O'donovan, M.C , Scientific Reports, 8 (1), art. no. 10168. PMID: 29977057 , 2018
• A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies D Gudrā, Shoaie, S.,, D Fridmanis, J Kloviņš, Wefer, H., I Silamiķelis, R Pečulis, I Kalniņa, I Elbere, I Radoviča-Spalviņa, Hultcrantz, R., Skenders, G., Leja, M., Engstrand, L , Gut, . Article in Press. PMID: 30242040 , 2018
• Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood Ni, G., Moser, G., Ripke, S., Neale,, J Kloviņš, Wray, N.R., Lee, S.H , American Journal of Human Genetics, 102 (6), pp. 1185-1194. PMID: 29754766 , 2018
• Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals. I Elbere, I Silamiķelis, M Ustinova, I Kalniņa, L Zaharenko, R Pečulis, Konrade I, Ciuculete DM, Zhukovsky C,, D Gudrā, I Radoviča-Spalviņa, D Fridmanis, Pirags V, Schiöth HB, J Kloviņš , Clinical Epigenetics , 2018
• Synthesis and evaluation of (E)-2-(5-phenylpent-2 en-4-ynamido)cyclohex-1-ene-1-carblate derivatives as HCA2 receptor agonoxyists Bobileva, O., Ikaunieks, M., Duburs, G.,, I Mandrika, R Petrovska, J Kloviņš, Loza, E , Bioorganic and Medicinal Chemistry, 25 (16), pp. 4314-4329 , 2017
• What do we know about underlying molecular mechanisms? D Fridmanis, A Roga, J Kloviņš, ACTH receptor (MC2R) specificity , Frontiers in Endocrinology, 8 (FEB), art. no. 13 , 2017
• Next-generation-sequencing-based identification of familial hypercholesterolemia-related mutations in subjects with increased LDL-C levels in a latvian population I Radoviča-Spalviņa, Latkovskis, G.,, I Silamiķelis, D Fridmanis, I Elbere, Ventins, K., Ozola, G., Erglis, A., J Kloviņš , BMC Medical Genetics, 16 (1), art. no. 86. , 2015
• Massive paralel sequencing in hypercholesterolemic patients of Latvia I Radoviča-Spalviņa, R.Berziņš, D.Silava, I Silamiķelis, D Fridmanis, J Kloviņš , European Conference of Human Genetics, Itālija, Milāna , 2014

• Conference thesis

• Symposium "Molecular Pathophysiology for Clinician: receptor-related disorders" management J Kloviņš , 16th European Society of Endocrinology 2014, Vroclova, Polija , 2014
• Baltic infrastructure collaboration – the high-level group in RI in Baltic countries J Kloviņš , Strengthening the Baltic - Nordic research collaboration, Tartu, Igaunija , 2014

Quick links

• Purchases
• Purchases archive
• Core Facilities
• Facilities and services
• EURAXESS